I always looked at where you stay as being where you sleep, shower and change... (and that other stuff too ;o). If you want to drink - get away from the hotel and go to Duval St. - (lower end), popular places like Sloppy Joes, Irish Kevin's, Rick's, Hogs Breath, etc... all fun places to drink and rip it up! Then, when the sun starts to come up, stumble back to your hotel away from the noise and commotion and get a couple hours sleep, a bath - and hit the beach (or pool) to "dry out". Plus, if you stay at Ocean Key or the Pier House, you'll pay big $$ for the location and could really spend that money elsewhere. And don't miss sunset celebration - Mallory Sq. - to the south / east of Ocean Key House, your GF will thank you for it!!