You can pick a hotel on Hwy 54 and be close to several places. I would recommending stopping by any restaurant or grocery store/Wal Mart and picking up a tourism guide. It will have all the bars marked out clearly (there are more than you would be able to hit in a week at the lake).
I would recommend Dog Days, Shorty Pants, Backwater Jacks, Horny Toad as a few hot spots on the Hwy 54 side. If you make it across the toll bridge, Franky & Louies and probably my favorite place.