I've done it a couple of times (when I had a running boat ). Since we just go up and down the TN river (for the most part) it's pretty simple. I'm sure that Matt (haulinvols) will put a cheat sheet (the GPS coordinates) together before the run.
There is only one spot that it is EXTREMELY important to follow the channel markers and it's really easy to know when you get there.
Man, I put alot of parenthesis in this post. Anyway, there is a registration discount and extra hand if you register and pay before the end of the month.