Going with a 4.600 bore...you might have 1 oversize left in the block.
And going with a longer throw crank, 4.5+...your cylinders and pistons will wear quicker.
I like the 4.500 bore with a 4.500 crank...hense 572CI
So it depends if your in the mood to toss the blocks at every rebuild lasting 200hrs or so.
Im not an engine builder but this is my opinon.