I drive a 2000 crewcab dually Ford 4x4, and have put 45000 miles on it. As a daily driver, the first thing you'll have to master is backing into parking spots. Diagonal parking is iffy, and parallel parking REAL fun. I find it awesome in the snow, as the extra width on the rear wheels actually helps keep it going straight when going over the humps that snowplows leave behind while changing lanes at 50mph.
I drive it to thru bank, Burger King, thru the parking structure at work, as long as I have 6'8" clearance.
Also, the 7.3L diesel package makes quite the tow vehicle. I have a slide-in camper that sits in the bed (2500lbs), and tow a 33' Fountain (8800lbs), plus the truck (6000lbs) and can use the cruise control most of the way down to Lake Cumberland! I get 16 or so mpg empty and 12mpg with a full load.
I hear that Ford has a new 6.0L diesel out this year that produces more HP and torque that the 7.3. Put a 6-speed manual tranny behind it and you can tow anything.