Howdy Bad Habit.
It all depends what you are looking for. The Ripley Maysville area is nice and has a few small resturants and marinas....you could make a trip out of it and start in Cincy and work your way up thru the dam/locks and wind up in Ripley (about 20min up river from Meldahl Dam). That is a nice run. Up river is bueatiful and will be pretty quite is my guess.
I do not know where to get some good charts. I have made that run several times and the only shallows I am aware of are in hte New Richmond area. They are marked and are still plenty deep to navigate a pleasure craft.