I would say something that requires less than 150# on the seat, but maybe its the over the nose pressure you need to be more concerned with. Bob M. could speculate better on this.
They break the axle and roller in hp500's I wouldn't use them with anything more than stock. I don't even put them back in for stock motors
I'm pretty sure the hp rollers never used the stock GM lifter , but I do remember them wrecking the Crane rollers and that may have had more to do with the spring than anything else.